Enzyme Details

Enzyme (Recommended) Name	ferrochelatase
Alternative names	protoheme ferro-lyase (protoporphyrin-forming) ferro-protoporphyrin chelatase iron chelatase heme synthetase heme synthase protoheme ferro-lyase
EC Classification	4.99.1.1
Classification	Lyases Other lyases Sole sub-subclass for lyases that do not belong in the other subclasses
Catalyses reactions	Fe2+ + Protoporphyrin <-> 2 H+ + Heme Zn2+ + Protoporphyrin <-> 2 H+ + Zinc protoporphyrin-9 Fe2+ + Mesoporphyrin IX <-> 2 H+ + Mesoheme Zn2+ + Mesoporphyrin IX <-> 2 H+ + Zinc mesoporphyrin IX
External links	Expasy KEGG IntEnz (EBI) IUBMB Reactome HepatoSys
	View all entries for EC Class 4.99.1.1