Reaction Details

Stochiometric Equation Fe2+ + Protoporphyrin <-> 2 H+ + Heme
Substrates
Fe2+
Protoporphyrin
Products
Heme
H+
Enzymes known to catalyse this reaction (curated information)
EC Numberin OrganismUniProt LinkPubMedID
4.99.1.1 Bos taurus UniProt 2310748
4.99.1.1 Gallus gallus UniProt 9808757
4.99.1.1 Homo sapiens UniProt 6425295
4.99.1.1 Homo sapiens UniProt 9808757
4.99.1.1 Pisum sativum UniProt 11853551
4.99.1.1 Rattus norvegicus UniProt 7309736
4.99.1.1 Xenopus laevis UniProt 9808757
Pathways Biosynthesis of cofactors
Biosynthesis of secondary metabolites
Metabolic pathways
Porphyrin and chlorophyll metabolism


View all entries for reaction Fe2+ + Protoporphyrin <-> 2 H+ + Heme