Pathway Details
Recommended name
2-Oxocarboxylic acid metabolism
Alternative names
Reactions
Oxalosuccinate <-> CO2 + 2-Oxoglutarate
NADP+ + Isocitrate <-> H+ + NADPH + Oxalosuccinate
Coenzyme A + Citrate <-> H2O + Acetyl-CoA + Oxaloacetate
Citrate <-> H2O + cis-Aconitate
NADP+ + Isocitrate <-> H+ + NADPH + CO2 + 2-Oxoglutarate
NAD+ + Isocitrate <-> NADH + H+ + CO2 + 2-Oxoglutarate
Citrate <-> Isocitrate
Isocitrate <-> H2O + cis-Aconitate
Coenzyme A + Homocitrate <-> H2O + Acetyl-CoA + 2-Oxoglutarate
Coenzyme A + 2-Isopropylmalate <-> H2O + Acetyl-CoA + alpha-Ketovaline
CO2 + (S)-2-Acetolactate <-> 2 Pyruvate
L-Alanine + 2-Oxoglutarate <-> Pyruvate + L-Glutamate
L-Glutamate + Acetyl-CoA <-> Coenzyme A + N-Acetyl-L-glutamate
L-Aspartate + 2-Oxoglutarate <-> L-Glutamate + Oxaloacetate
ATP + L-Aspartate <-> ADP + 4-Phospho-L-aspartate
H2O + N2-Acetyl-L-ornithine <-> Acetate + L-Ornithine
L-Phenylalanine + 2-Oxoglutarate <-> L-Glutamate + Phenylpyruvate
L-Tyrosine + 2-Oxoglutarate <-> L-Glutamate + 3-(4-Hydroxyphenyl)pyruvate
L-Leucine + 2-Oxoglutarate <-> L-Glutamate + 4-Methyl-2-oxopentanoate
2,3-Dihydroxy-3-methylbutanoate <-> H2O + alpha-Ketovaline
L-Valine + 2-Oxoglutarate <-> L-Glutamate + alpha-Ketovaline
CO2 + 4-Methyl-2-oxopentanoate <-> 3-Carboxy-4-methyl-2-oxopentanoate
NAD+ + Homoisocitrate <-> NADH + H+ + CO2 + 2-Oxoadipate
Oxaloglutarate <-> CO2 + 2-Oxoadipate
2-Oxoglutarate + L-2-Aminoadipate <-> L-Glutamate + 2-Oxoadipate
L-Isoleucine + 2-Oxoglutarate <-> L-Glutamate + 3-Methyl-2-oxopentanoate
L-Glutamate + N2-Acetyl-L-ornithine <-> L-Ornithine + N-Acetyl-L-glutamate
2-Oxoglutarate + N2-Acetyl-L-ornithine <-> L-Glutamate + N-Acetyl-L-glutamate 5-semialdehyde
Phosphate + NADP+ + L-Aspartate 4-semialdehyde <-> H+ + NADPH + 4-Phospho-L-aspartate
ATP + N-Acetyl-L-glutamate <-> ADP + N-Acetyl-L-glutamyl 5-phosphate
3'-Phosphoadenylyl sulfate + Desulfoglucotropeolin <-> Adenosine 3',5'-bisphosphate + Glucotropeolin
Phosphate + NADP+ + N-Acetyl-L-glutamate 5-semialdehyde <-> H+ + NADPH + N-Acetyl-L-glutamyl 5-phosphate
Homocitrate <-> H2O + But-1-ene-1,2,4-tricarboxylate
D-Citramalate <-> H2O + 2-Methylmaleate
H2O + 2-Methylmaleate <-> D-erythro-3-Methylmalate
2-Isopropylmalate <-> H2O + 2-Isopropylmaleate
3-Isopropylmalate <-> H2O + 2-Isopropylmaleate
Homoisocitrate <-> H2O + But-1-ene-1,2,4-tricarboxylate
NAD+ + 3-Isopropylmalate <-> NADH + H+ + 3-Carboxy-4-methyl-2-oxopentanoate
(R)-2,3-Dihydroxy-3-methylbutanoate <-> H2O + alpha-Ketovaline
NAD+ + Homoisocitrate <-> NADH + H+ + Oxaloglutarate
CO2 + 2-Acetolactate <-> 2 Pyruvate
Pyruvate + 2-Oxobutyrate <-> CO2 + (S)-2-Aceto-2-hydroxybutanoate
L-Glutamate + L-Aspartate 4-semialdehyde <-> 2-Oxoglutarate + L-2,4-Diaminobutanoate
(S)-2-Acetolactate <-> 3-Hydroxy-3-methyl-2-oxobutanoate
NADP+ + (R)-2,3-Dihydroxy-3-methylbutanoate <-> H+ + NADPH + 3-Hydroxy-3-methyl-2-oxobutanoate
Pyruvate + H2O + Acetyl-CoA <-> Coenzyme A + D-Citramalate
L-Isoleucine + 2-Oxoglutarate <-> L-Glutamate + (S)-3-Methyl-2-oxopentanoate
NADP+ + (R)-2,3-Dihydroxy-3-methylpentanoate <-> H+ + NADPH + (R)-3-Hydroxy-3-methyl-2-oxopentanoate
(S)-2-Aceto-2-hydroxybutanoate <-> (R)-3-Hydroxy-3-methyl-2-oxopentanoate
(R)-2,3-Dihydroxy-3-methylpentanoate <-> H2O + (S)-3-Methyl-2-oxopentanoate
NAD+ + 3-Isopropylmalate <-> NADH + H+ + CO2 + 4-Methyl-2-oxopentanoate
2 H+ + L-Tryptophan + 2 NADPH + 2 O2 <-> 3 H2O + 2 NADP+ + CO2 + Indole-3-acetaldoxime
Classification
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