Reaction Details
Reaction ID
269
Stochiometric Equation
NADP+ + Isocitrate <-> H+ + NADPH + CO2 + 2-Oxoglutarate
Substrates
NADP+
Isocitrate
Products
CO2
NADPH
2-Oxoglutarate
H+
Enzymes known to
catalyse this reaction
(curated information)
EC Number
in Organism
UniProtKB Link
PubMedID
1.1.1.42
Acidithiobacillus thiooxidans
UniProtKB
12204383
1.1.1.42
Archaeoglobus fulgidus
UniProtKB
17401542
1.1.1.42
Bacillus subtilis
UniProtKB
11751849
1.1.1.42
Bifidobacterium longum
UniProtKB
26927087
1.1.1.42
Bos taurus
UniProtKB
7447463
1.1.1.42
Escherichia coli
UniProtKB
11751849
1.1.1.42
Escherichia coli
UniProtKB
14731279
1.1.1.42
Escherichia coli
UniProtKB
17401542
1.1.1.42
Escherichia coli
UniProtKB
27406240
1.1.1.42
Escherichia coli
UniProtKB
7761851
1.1.1.42
Escherichia coli
UniProtKB
7819221
1.1.1.42
Escherichia coli
UniProtKB
8369299
1.1.1.42
Escherichia coli
UniProtKB
8524825
1.1.1.42
Halobacterium volcanii
UniProtKB
12007799
1.1.1.42
Halobacterium volcanii
UniProtKB
8593959
1.1.1.42
Helicobacter pylori
UniProtKB
10091606
1.1.1.42
Homo sapiens
UniProtKB
10521434
1.1.1.42
Homo sapiens
UniProtKB
12176063
1.1.1.42
Homo sapiens
UniProtKB
16909
1.1.1.42
Homo sapiens
UniProtKB
19359588
1.1.1.42
Homo sapiens
UniProtKB
19935646
1.1.1.42
Homo sapiens
UniProtKB
20142433
1.1.1.42
Homo sapiens
UniProtKB
20975740
1.1.1.42
Homo sapiens
UniProtKB
23731180
1.1.1.42
Homo sapiens
UniProtKB
24668804
1.1.1.42
Homo sapiens
UniProtKB
25391653
1.1.1.42
Homo sapiens
UniProtKB
25502799
1.1.1.42
Homo sapiens
UniProtKB
26436839
1.1.1.42
Homo sapiens
UniProtKB
28091
1.1.1.42
Homo sapiens
UniProtKB
28330869
1.1.1.42
Homo sapiens
UniProtKB
28373671
1.1.1.42
Homo sapiens
UniProtKB
4401241
1.1.1.42
Homo sapiens
UniProtKB
4411607
1.1.1.42
Homo sapiens
UniProtKB
4429550
1.1.1.42
Mycobacterium tuberculosis
UniProtKB
23409873
1.1.1.42
Oryctolagus cuniculus
UniProtKB
4429550
1.1.1.42
Pisum sativum
UniProtKB
14507432
1.1.1.42
Plasmodium falciparum
UniProtKB
12694190
1.1.1.42
Rattus norvegicus
UniProtKB
30053395
1.1.1.42
Rattus norvegicus
UniProtKB
3207422
1.1.1.42
Rattus rattus
UniProtKB
16489927
1.1.1.42
Rhodomicrobium vannielii
UniProtKB
1935983
1.1.1.42
Saccharomyces cerevisiae
UniProtKB
15001388
1.1.1.42
Saccharomyces cerevisiae
UniProtKB
15574419
1.1.1.42
Saccharomyces cerevisiae
UniProtKB
25502799
1.1.1.42
Saccharomyces cerevisiae
UniProtKB
9452501
1.1.1.42
Streptococcus suis
UniProtKB
21586311
1.1.1.42
Streptomyces lividans
UniProtKB
19631711
1.1.1.42
Sulfolobus solfataricus
UniProtKB
8593959
1.1.1.42
Sus scrofa
UniProtKB
10681542
1.1.1.42
Sus scrofa
UniProtKB
10694384
1.1.1.42
Sus scrofa
UniProtKB
11969425
1.1.1.42
Sus scrofa
UniProtKB
12054490
1.1.1.42
Sus scrofa
UniProtKB
14512428
1.1.1.42
Sus scrofa
UniProtKB
15005617
1.1.1.42
Sus scrofa
UniProtKB
15576556
1.1.1.42
Sus scrofa
UniProtKB
15975917
1.1.1.42
Sus scrofa
UniProtKB
2354193
1.1.1.42
Sus scrofa
UniProtKB
4151308
1.1.1.42
Sus scrofa
UniProtKB
8936592
1.1.1.42
Teladorsagia circumcincta
UniProtKB
21320492
1.1.1.42
Yarrowia lipolytica
UniProtKB
25502799
1.1.1.42
Zea mays
UniProtKB
10847
Pathways
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids
Carbon fixation pathways in prokaryotes
Carbon metabolism
Citrate cycle (TCA cycle)
Glutathione metabolism
Metabolic pathways
Microbial metabolism in diverse environments
External Links
KEGG-Pathway-ID
map01210
map01230
map00720
map01200
map00020
map00480
map01100
map01120
KEGG-Reaction-ID
R00267
MetaNetX-Reaction-ID
MNXR100781
Rhea-Reaction-ID
19629
19631
19632
19630
View all entries for reaction NADP+ + Isocitrate <-> H+ + NADPH + CO2 + 2-Oxoglutarate
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