Reaction Details

Reaction ID

1380

Stochiometric Equation

ATP + (R)-5-Diphosphomevalonate <-> ADP + Phosphate + CO2 + Isopentenyl diphosphate

Substrates

ATP

(R)-5-Diphosphomevalonate

Products

ADP

CO2

Phosphate

Isopentenyl diphosphate

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
4.1.1.33	Arachis hypogaea	UniProtKB	2528059
4.1.1.33	Hevea brasiliensis	UniProtKB	4333851
4.1.1.33	Homo sapiens	UniProtKB	8188698
4.1.1.33	Homo sapiens	UniProtKB	8626466
4.1.1.33	Homo sapiens	UniProtKB	9392419
4.1.1.33	Rattus norvegicus	UniProtKB	9348097
4.1.1.33	Saccharomyces cerevisiae	UniProtKB	15169949

Pathways

Biosynthesis of secondary metabolites
Metabolic pathways
Terpenoid backbone biosynthesis

External Links

KEGG-Pathway-ID

map01110
map01100
map00900

KEGG-Reaction-ID

R01121

MetaNetX-Reaction-ID

MNXR153393

Rhea-Reaction-ID

23735 23734 23733 23732

MetaCyc-Reaction-ID

DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN