Reaction Details



 Reaction ID 2092
 Stochiometric Equation 2 NADP+ + Coenzyme A + (R)-Mevalonate <-> 2 H+ + 2 NADPH + 3-Hydroxy-3-methylglutaryl-CoA
 Substrates
NADP+
Coenzyme A
(R)-Mevalonate
 Products
NADPH
3-Hydroxy-3-methylglutaryl-CoA
H+
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
1.1.1.34 Arachis hypogaea UniProtKB 2528059
1.1.1.34 Enterococcus faecalis UniProtKB 11914342
1.1.1.34 Homo sapiens UniProtKB 10392455
1.1.1.34 Homo sapiens UniProtKB 8188698
1.1.1.34 Mesocricetus auratus UniProtKB 8120043
1.1.1.34 Mus musculus UniProtKB 10392455
1.1.1.34 Trypanosoma cruzi UniProtKB 9521823
 Pathways Biosynthesis of secondary metabolites
Metabolic pathways
Terpenoid backbone biosynthesis
 External Links
 KEGG-Pathway-ID map01110
map01100
map00900
 KEGG-Reaction-ID R02082
 MetaNetX-Reaction-ID MNXR145221


View all entries for reaction 2 NADP+ + Coenzyme A + (R)-Mevalonate <-> 2 H+ + 2 NADPH + 3-Hydroxy-3-methylglutaryl-CoA

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