Reaction Details
Reaction ID
2736
Stochiometric Equation
H+ + NADPH + O2 + Squalene <-> H2O + NADP+ + (S)-2,3-Epoxysqualene
Substrates
H+
O2
NADPH
Squalene
Products
NADP+
H2O
(S)-2,3-Epoxysqualene
Enzymes known to
catalyse this reaction
(curated information)
EC Number
in Organism
UniProtKB Link
PubMedID
1.14.14.17
Homo sapiens
UniProtKB
10666321
1.14.14.17
Homo sapiens
UniProtKB
30626872
1.14.14.17
Rattus norvegicus
UniProtKB
17112472
1.14.14.17
Rattus norvegicus
UniProtKB
7595073
1.14.14.17
Saccharomyces cerevisiae
UniProtKB
8358382
Pathways
Biosynthesis of secondary metabolites
Metabolic pathways
Sesquiterpenoid and triterpenoid biosynthesis
Steroid biosynthesis
External Links
KEGG-Pathway-ID
map01110
map01100
map00909
map00100
KEGG-Reaction-ID
R02874
MetaNetX-Reaction-ID
MNXR146441
Reactome-Reaction-ID
R-RNO-191299
R-TGU-191299
R-OSA-191299
R-DRE-191299
R-CFA-191299
R-GGA-191299
R-ATH-191299
R-SSC-191299
R-DDI-191299
R-HSA-191299
R-BTA-191299
R-SCE-191299
R-MMU-191299
R-SPO-191299
R-XTR-191299
View all entries for reaction H+ + NADPH + O2 + Squalene <-> H2O + NADP+ + (S)-2,3-Epoxysqualene
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