Reaction Details

Reaction ID

572

Stochiometric Equation

ATP + L-Aspartate + L-Citrulline <-> Diphosphate + AMP + N(omega)-(L-Arginino)succinate

Substrates

L-Citrulline

ATP

L-Aspartate

Products

AMP

N(omega)-(L-Arginino)succinate

Diphosphate

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
6.3.4.5	Bos taurus	UniProtKB	6547814
6.3.4.5	Bos taurus	UniProtKB	885853
6.3.4.5	Homo sapiens	UniProtKB	2791302
6.3.4.5	Homo sapiens	UniProtKB	518841
6.3.4.5	Homo sapiens	UniProtKB	7087958
6.3.4.5	Rattus norvegicus	UniProtKB	5300
6.3.4.5	Sus scrofa	UniProtKB	9734336

Pathways

Alanine, aspartate and glutamate metabolism
Arginine and Proline metabolism
Arginine biosynthesis
Biosynthesis of amino acids
Biosynthesis of secondary metabolites
Insulin signaling pathway
Metabolic pathways
Urea cycle

External Links

KEGG-Pathway-ID

map00250
map00330
map00220
map01230
map01110
map04910
map01100

KEGG-Reaction-ID

R01954

MetaNetX-Reaction-ID

MNXR138060

Rhea-Reaction-ID

10933 10934 10932 10935

MetaCyc-Reaction-ID

ARGSUCCINSYN-RXN

View all entries for reaction ATP + L-Aspartate + L-Citrulline <-> Diphosphate + AMP + N(omega)-(L-Arginino)succinate