Reaction Details



 Reaction ID 669
 Stochiometric Equation H2O + 4 Porphobilinogen <-> 4 NH3 + Hydroxymethylbilane
 Substrates
Porphobilinogen
H2O
 Products
Hydroxymethylbilane
NH3
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
2.5.1.61 Escherichia coli UniProtKB 2025226
2.5.1.61 Escherichia coli UniProtKB 3548707
2.5.1.61 Homo sapiens UniProtKB 23815679
2.5.1.61 Rattus norvegicus UniProtKB 1418238
 Pathways Biosynthesis of cofactors
Biosynthesis of secondary metabolites
Metabolic pathways
Microbial metabolism in diverse environments
Porphyrin and chlorophyll metabolism
 External Links
 KEGG-Pathway-ID map01240
map01110
map01100
map01120
map00860
 KEGG-Reaction-ID R00084
 MetaNetX-Reaction-ID MNXR100658
 Rhea-Reaction-ID 13185 13186 13187 13188
 Reactome-Reaction-ID R-GGA-189406 R-PFA-189406 R-CFA-189406 R-ATH-189406 R-DDI-189406 R-SSC-189406 R-XTR-189406 R-RNO-189406 R-MMU-189406 R-OSA-189406 R-SCE-189406 R-GGA-421439 R-DME-189406 R-DRE-189406 R-HSA-189406 R-SPO-189406 R-TGU-189406 R-BTA-189406
 MetaCyc-Reaction-ID OHMETHYLBILANESYN-RXN


View all entries for reaction H2O + 4 Porphobilinogen <-> 4 NH3 + Hydroxymethylbilane

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