Reaction Details
Reaction ID
8163
Stochiometric Equation
NAD+ + Coenzyme A + 2-Oxoglutarate <-> NADH + H+ + CO2 + Succinyl-CoA
Substrates
2-Oxoglutarate
NAD+
Coenzyme A
Products
H+
Succinyl-CoA
NADH
CO2
Enzymes known to
catalyse this reaction
(curated information)
EC Number
in Organism
UniProtKB Link
PubMedID
1.2.4.2
Rattus norvegicus
UniProtKB
3207422
1.2.4.2
Solanum tuberosum
UniProtKB
16667685
1.2.4.2
Teladorsagia circumcincta
UniProtKB
21320492
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Acrididae
UniProtKB
7032511
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Azotobacter vinelandii
UniProtKB
10848975
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Columba sp.
UniProtKB
7032511
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Corynebacterium glutamicum
UniProtKB
20675489
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Escherichia coli
UniProtKB
6985904
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Escherichia coli
UniProtKB
7032511
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Fasciola hepatica
UniProtKB
8898339
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Homo sapiens
UniProtKB
12176063
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Homo sapiens
UniProtKB
2087902
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Homo sapiens
UniProtKB
25210035
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Homo sapiens
UniProtKB
4462577
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Homo sapiens
UniProtKB
7032511
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Lucilia sericata
UniProtKB
7032511
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Oncorhynchus mykiss
UniProtKB
7032511
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Rattus norvegicus
UniProtKB
4312474
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Rattus norvegicus
UniProtKB
4462577
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Rattus norvegicus
UniProtKB
7032511
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Solanum tuberosum
UniProtKB
7032511
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Sus scrofa
UniProtKB
39549
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Sus scrofa
UniProtKB
4361738
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Sus scrofa
UniProtKB
5812959
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Sus scrofa
UniProtKB
6020442
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Sus scrofa
UniProtKB
6985904
Complex:
1.2.4.2
/
2.3.1.61
/
1.8.1.4
Xenopus laevis
UniProtKB
7032511
Complex:
1.2.4.4
/
2.3.1.168
/
1.8.1.4
Homo sapiens
UniProtKB
3593587
Complex:
1.2.4.4
/
2.3.1.168
/
1.8.1.4
Rattus norvegicus
UniProtKB
3571202
Pathways
Biosynthesis of secondary metabolites
Carbon metabolism
Metabolic pathways
Microbial metabolism in diverse environments
External Links
KEGG-Pathway-ID
map01110
map01200
map01100
map01120
KEGG-Reaction-ID
R08549
MetaNetX-Reaction-ID
MNXR95655
Rhea-Reaction-ID
27789
27788
27787
27786
Reactome-Reaction-ID
R-XTR-71401
R-TGU-71401
R-RNO-71401
R-ATH-71401
R-SCE-71401
R-MMU-71401
R-GGA-373042
R-SSC-71401
R-CEL-71401
R-DME-71401
R-OSA-71401
R-HSA-71401
R-DRE-71401
R-GGA-71401
R-CFA-71401
R-PFA-71401
R-BTA-71401
R-DDI-71401
R-SPO-71401
MetaCyc-Reaction-ID
2OXOGLUTARATEDEH-RXN
View all entries for reaction NAD+ + Coenzyme A + 2-Oxoglutarate <-> NADH + H+ + CO2 + Succinyl-CoA
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