Reaction Details

Reaction ID

9177

Stochiometric Equation

H2O + GTP <-> Formate + 7,8-Dihydroneopterin 3'-triphosphate

Substrates

H2O

GTP

Products

Formate

7,8-Dihydroneopterin 3'-triphosphate

Enzymes known to
catalyse this reaction
(curated information)

EC Number	in Organism	UniProtKB Link	PubMedID
3.5.4.16	Helicobacter pylori	UniProtKB	23825549
3.5.4.16	Homo sapiens	UniProtKB	2500984
3.5.4.16	Homo sapiens	UniProtKB	3753653
3.5.4.16	Rattus norvegicus	UniProtKB	2557335
3.5.4.16	Solanum lycopersicum	UniProtKB	12221287

Pathways

Biosynthesis of cofactors

External Links

KEGG-Pathway-ID

map01240

KEGG-Reaction-ID

R00424

MetaNetX-Reaction-ID

MNXR145137

Rhea-Reaction-ID

17474 17473 17476 17475

MetaCyc-Reaction-ID

GTP-CYCLOHYDRO-I-RXN