Reaction Details
Reaction ID
95
Stochiometric Equation
H2O + Glycine + 5,10-Methylenetetrahydrofolate <-> L-Serine + 5,6,7,8-Tetrahydrofolate
Substrates
Glycine
H2O
5,10-Methylenetetrahydrofolate
Products
5,6,7,8-Tetrahydrofolate
L-Serine
Enzymes known to
catalyse this reaction
(curated information)
EC Number
in Organism
UniProtKB Link
PubMedID
2.1.2.1
Arabidopsis thaliana
UniProtKB
20518745
2.1.2.1
Arabidopsis thaliana
UniProtKB
31873125
2.1.2.1
Bombyx mori
UniProtKB
31298425
2.1.2.1
Escherichia coli
UniProtKB
19019081
2.1.2.1
Escherichia coli
UniProtKB
19883126
2.1.2.1
Escherichia coli
UniProtKB
3891721
2.1.2.1
Geobacillus stearothermophilus
UniProtKB
12089472
2.1.2.1
Glycine max
UniProtKB
16664855
2.1.2.1
Homo sapiens
UniProtKB
24698160
2.1.2.1
Homo sapiens
UniProtKB
25619277
2.1.2.1
Macaca radiata
UniProtKB
6787050
2.1.2.1
Macaca radiata
UniProtKB
6821365
2.1.2.1
Oryctolagus cuniculus
UniProtKB
9675060
2.1.2.1
Ovis aries
UniProtKB
12089472
2.1.2.1
Ovis aries
UniProtKB
7607226
2.1.2.1
Plasmodium falciparum
UniProtKB
19591881
2.1.2.1
Plasmodium vivax
UniProtKB
19549189
2.1.2.1
Rattus norvegicus
UniProtKB
3110140
2.1.2.1
Rattus norvegicus
UniProtKB
5650436
2.1.2.1
Trypanosoma cruzi
UniProtKB
10651807
2.1.2.1
Vigna radiata
UniProtKB
16662139
Pathways
Biosynthesis of amino acids
Biosynthesis of cofactors
Biosynthesis of secondary metabolites
Carbon metabolism
Cyanoamino acid metabolism
Glycine, Serine and Threonine metabolism
Glyoxylate and Dicarboxylate metabolism
Metabolic pathways
Methane metabolism
Microbial metabolism in diverse environments
One carbon pool by folate
External Links
KEGG-Pathway-ID
map01230
map01240
map01110
map01200
map00460
map00260
map00630
map01100
map00680
map01120
map00670
KEGG-Reaction-ID
R00945
MetaNetX-Reaction-ID
MNXR100142
Rhea-Reaction-ID
15481
15483
15482
15484
View all entries for reaction H2O + Glycine + 5,10-Methylenetetrahydrofolate <-> L-Serine + 5,6,7,8-Tetrahydrofolate
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