Reaction Details

Stochiometric Equation H2O + 5,10-Methylenetetrahydrofolate + 3-Methyl-2-oxopentanoate <-> 5,6,7,8-Tetrahydrofolate + 3-(Hydroxymethyl)-3-methyl-2-oxopentanoic acid
Substrates
H2O
5,10-Methylenetetrahydrofolate
3-Methyl-2-oxopentanoate
Products
5,6,7,8-Tetrahydrofolate
3-(Hydroxymethyl)-3-methyl-2-oxopentanoic acid
Enzymes known to catalyse this reaction (curated information)
EC Numberin OrganismUniProt LinkPubMedID
2.1.2.11 Escherichia coli UniProt 6463
Pathways


View all entries for reaction H2O + 5,10-Methylenetetrahydrofolate + 3-Methyl-2-oxopentanoate <-> 5,6,7,8-Tetrahydrofolate + 3-(Hydroxymethyl)-3-methyl-2-oxopentanoic acid