Enzyme Details

Enzyme (Recommended) Name gamma-butyrobetaine dioxygenase
Alternative names 4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)
alpha-butyrobetaine hydroxylase
gamma-butyrobetaine hydroxylase
butyrobetaine hydroxylase
EC Classification 1.14.11.1
Classification
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
Catalyses reactions
O2 + 2-Oxoglutarate + 4-Trimethylammoniobutanoate <-> CO2 + Succinate + Carnitine
3-Dehydroxycarnitine <-> Carnitine
O2 + 2-Oxoglutarate + 4-Trimethylammoniobutanoate <-> CO2 + L-Carnitine + Succinate
O2 + 4-Trimethylammoniobutanoate + 3-Bromo-2-ketoglutarate <-> CO2 + L-Carnitine + 3-Bromo-succinate
External links Expasy
KEGG
IntEnz (EBI)
IUBMB
Reactome
HepatoSys


View all entries for EC Class 1.14.11.1