Pathway Details

Recommended name

Pyruvate metabolism

Alternative names

Reactions

CO2 + 2-(alpha-Hydroxyethyl)thiamine diphosphate <-> Pyruvate + Thiamine diphosphate

H2O + NADP+ + Methylglyoxal <-> Pyruvate + H+ + NADPH

NAD+ + H2O + D-Lactaldehyde <-> NADH + H+ + D-Lactate

Phosphoenolpyruvate + CO2 + XDP <-> XTP + Oxaloacetate

H+ + NADPH + Succinate semialdehyde <-> NADP+ + 4-Hydroxybutanoate

Pyruvate + NADP+ + Coenzyme A <-> H+ + NADPH + CO2 + Acetyl-CoA

2 Ferricytochrome c + D-Lactate <-> Pyruvate + 2 Ferrocytochrome c

Pyruvate + H2O + Ferricytochrome b1 <-> CO2 + Acetate + Ferrocytochrome b1

GTP + Oxaloacetate <-> Phosphoenolpyruvate + CO2 + GDP

Diphosphate + Acetate <-> Phosphate + Acetyl phosphate

H2O + Acetyl phosphate <-> Phosphate + Acetate

Phosphoenolpyruvate + Inosine-1-oxide 5'-diphosphate <-> Pyruvate + Inosine-1-oxide 5'-triphosphate

NAD+ + L-Malate <-> NADH + H+ + Oxaloacetate

H2O + (R)-S-Lactoylglutathione <-> Reduced glutathione + D-Lactate

CO2 + Acetyl-CoA + Reduced ferredoxin <-> Pyruvate + Coenzyme A + Oxidized ferredoxin

Pyruvate + CO2 <-> Enol-Oxaloacetate

Oxaloacetate <-> Pyruvate + CO2

L-Lactate + Acceptor <-> Pyruvate + Reduced acceptor

Pyruvate + dGTP <-> Phosphoenolpyruvate + dGDP

NADP+ + L-Malate <-> Pyruvate + H+ + NADPH + CO2

Phosphoenolpyruvate + Isoguanosine 5'-diphosphate <-> Pyruvate + Isoguanosine 5'-triphosphate

Coenzyme A + Homocitrate <-> H2O + Acetyl-CoA + 2-Oxoglutarate

Pyruvate + ATP + H2O <-> Phosphoenolpyruvate + Phosphate + AMP

Phosphoenolpyruvate + Adenosine-1-oxide 5'-diphosphate <-> Pyruvate + Adenosine-1-oxide 5'-triphosphate

Coenzyme A + 2-Propylmalate <-> Acetyl-CoA + 2-Oxopentanoate

D-Lactate + Acceptor <-> Pyruvate + Reduced acceptor

NAD+ + Coenzyme A + Acetaldehyde <-> NADH + H+ + Acetyl-CoA

H2O + Acetyl-CoA <-> Coenzyme A + Acetate

Pyruvate + NTP <-> Phosphoenolpyruvate + NDP

NAD+ + Dihydrolipoamide <-> NADH + H+ + Lipoamide

Pyruvate <-> CO2 + Acetaldehyde

(R)-S-Lactoylglutathione <-> Reduced glutathione + Methylglyoxal

H2O + Methylglyoxal + thio-NAD+ <-> Pyruvate + H+ + thio-NADH

L-Lactate <-> D-Lactate

NAD+ + Ethanol <-> NADH + H+ + Acetaldehyde

Pyruvate + ATP + Phosphate <-> Phosphoenolpyruvate + Diphosphate + AMP

O2 + L-Lactate <-> H2O + CO2 + Acetate

H2O + Acetaldehyde + PQQ <-> Acetate + PQQH2

Phosphoenolpyruvate + 1,N6-Ethenoadenosine 5'-diphosphate <-> Pyruvate + 1,N6-Ethenoadenosine 5'-triphosphate

NAD+ + D-Lactaldehyde <-> NADH + H+ + Methylglyoxal

Glycerone phosphate <-> Phosphate + Methylglyoxal

H2O + Methylglyoxal + 3-Acetylpyridine-adenine dinucleotide <-> Pyruvate + H+ + Reduced 3-acetylpyridine-adenine dinucleotide

ATP + Hydrogencarbonate + Holo-[carboxylase] <-> ADP + Phosphate + Carboxybiotin-carboxyl-carrier protein

Pyruvate + GTP <-> Phosphoenolpyruvate + GDP

D-Lactate + 2 Ferricytochrome c-553 <-> Pyruvate + 2 Ferrocytochrome c-553

ITP + Oxaloacetate <-> Phosphoenolpyruvate + CO2 + IDP

Succinate + Ubiquinone <-> Fumarate + Ubiquinol

H2O + 4-Nitrophenyl phosphate <-> Phosphate + p-Nitrophenol

NADP+ + L-Lactaldehyde <-> H+ + NADPH + Methylglyoxal

Acetyl-CoA + Propanoate <-> Acetate + Propanoyl-CoA

Pyruvate + dATP <-> Phosphoenolpyruvate + dADP

Acetyl-CoA + Formate <-> Pyruvate + Coenzyme A

ATP + Acetyl-CoA + Hydrogencarbonate <-> ADP + Phosphate + Malonyl-CoA

Pyruvate + H+ + NADPH <-> NADP+ + Lactate

Phosphate + Acetyl-CoA <-> Coenzyme A + Acetyl phosphate

L-Lactate <-> Formate + Acetaldehyde

Pyruvate + ATP <-> Phosphoenolpyruvate + ADP

Coenzyme A + 5'-O-[acetoxy(hydroxy)phosphoryl]adenosine <-> AMP + Acetyl-CoA

NADP+ + 1,2-Propanediol <-> H+ + NADPH + Lactaldehyde

NAD+ + H2O + Methylglyoxal <-> Pyruvate + NADH + H+

H2O + Acetyl-CoA + 2-Oxopentanoate <-> Coenzyme A + 2-Propylmalate

Pyruvate + ITP <-> Phosphoenolpyruvate + IDP

Ethanol + NADP+ <-> H+ + NADPH + Acetaldehyde

NADP+ + Glycolate <-> H+ + NADPH + Glyoxylate

H2O + Acetylenedicarboxylate <-> Pyruvate + CO2

Coenzyme A + (R)-2-Ethylmalate <-> H2O + Acetyl-CoA + 2-Oxobutyrate

Acetate + Succinyl-CoA <-> Acetyl-CoA + Succinate

2 Acetyl-CoA <-> Coenzyme A + Acetoacetyl-CoA

NAD+ + L-Lactate <-> Pyruvate + NADH + H+

Phosphoenolpyruvate + 8-Bromoadenosine 5'-diphosphate <-> Pyruvate + 8-Bromoadenosine 5'-triphosphate

ATP + Acetate <-> ADP + Acetyl phosphate

L-Malate <-> H2O + Fumarate

NAD+ + H2O + L-Lactaldehyde <-> NADH + H+ + L-Lactate

L-Malate <-> CO2 + L-Lactate

Phosphoenolpyruvate + XDP <-> Pyruvate + XTP

Enol-Oxaloacetate <-> H2O + Acetylenedicarboxylate

L-Lactate + Oxaloacetate <-> Pyruvate + Malate

Coenzyme A + 2-Isopropylmalate <-> H2O + Acetyl-CoA + alpha-Ketovaline

Coenzyme A + L-Malate <-> H2O + Acetyl-CoA + Glyoxylate

H2O + [Pyruvate dehydrogenase (lipoamide)] phosphate <-> Phosphate + [Pyruvate dehydrogenase (lipoamide)]

NADP+ + L-Malate <-> H+ + NADPH + Oxaloacetate

L-Citramalyl-CoA <-> Pyruvate + Acetyl-CoA

L-Lactate + 2 Ferricytochrome c <-> Pyruvate + 2 Ferrocytochrome c

Pyruvate + O2 + Coenzyme A <-> CO2 + Acetyl-CoA + H2O2

NAD+ + Reduced glutathione + D-Lactaldehyde <-> NADH + H+ + (R)-S-Lactoylglutathione

H2O + NADP+ + Acetaldehyde <-> H+ + NADPH + Acetate

H2O + Acetaldehyde + Acceptor <-> Acetate + Reduced acceptor

ATP + Coenzyme A + Acetate <-> ADP + Phosphate + Acetyl-CoA

FAD + L-Malate <-> Oxaloacetate + FADH2

NAD+ + L-Malate <-> Pyruvate + NADH + H+ + CO2

ATP + Oxaloacetate <-> Phosphoenolpyruvate + ADP + CO2

O2 + L-Malate <-> H2O2 + Oxaloacetate

NAD+ + D-Lactate <-> Pyruvate + NADH + H+

Pyruvate + NAD+ + Coenzyme A <-> NADH + H+ + CO2 + Acetyl-CoA

NAD+ + 1,2-Propanediol <-> NADH + H+ + L-Lactaldehyde

NAD+ + H2O + Acetaldehyde <-> NADH + H+ + Acetate

Pyruvate + ATP + Hydrogencarbonate <-> ADP + Phosphate + Oxaloacetate

Phosphate + Oxaloacetate <-> Phosphoenolpyruvate + H2O + CO2

Diphosphate + Oxaloacetate <-> Phosphoenolpyruvate + Phosphate + CO2

Pyruvate + Phosphate + O2 <-> CO2 + Acetyl phosphate + H2O2

NAD+ + Lactaldehyde <-> NADH + H+ + Methylglyoxal

H2O + S-Lactoylglutathione <-> Reduced glutathione + Lactate

ATP + Acetate <-> Diphosphate + 5'-O-[acetoxy(hydroxy)phosphoryl]adenosine

Classification

Carbohydrate Metabolism