Reaction Details
Reaction ID
61
Stochiometric Equation
NAD+ + L-Lactate <-> Pyruvate + NADH + H+
Substrates
L-Lactate
NAD+
Products
NADH
H+
Pyruvate
Enzymes known to
catalyse this reaction
(curated information)
EC Number
in Organism
UniProtKB Link
PubMedID
1.1.1
Lactobacillus confusus
UniProtKB
9153075
1.1.1.27
Acholeplasma laidlawii
UniProtKB
4712565
1.1.1.27
Anas platyrhynchos
UniProtKB
6022861
1.1.1.27
Bacillus subtilis
UniProtKB
17586670
1.1.1.27
Bos taurus
UniProtKB
14213346
1.1.1.27
Bos taurus
UniProtKB
6022861
1.1.1.27
Bufo calamita
UniProtKB
1714364
1.1.1.27
Enterococcus faecalis
UniProtKB
-
1.1.1.27
Enterococcus faecalis
UniProtKB
-
1.1.1.27
Enterococcus faecalis
UniProtKB
17595
1.1.1.27
Enterococcus faecalis
UniProtKB
3103687
1.1.1.27
Enterococcus faecalis
UniProtKB
3917918
1.1.1.27
Enterococcus faecalis
UniProtKB
4314543
1.1.1.27
Escherichia coli
UniProtKB
14503880
1.1.1.27
Gallus gallus
UniProtKB
14213346
1.1.1.27
Gallus gallus
UniProtKB
6022861
1.1.1.27
Geobacillus stearothermophilus
UniProtKB
-
1.1.1.27
Geobacillus stearothermophilus
UniProtKB
7703235
1.1.1.27
Geobacillus stearothermophilus
UniProtKB
8251493
1.1.1.27
Geobacillus stearothermophilus
UniProtKB
9051732
1.1.1.27
Hippoglossus stenolepis
UniProtKB
6022861
1.1.1.27
Homo sapiens
UniProtKB
10388846
1.1.1.27
Homo sapiens
UniProtKB
21042731
1.1.1.27
Homo sapiens
UniProtKB
7449128
1.1.1.27
Homo sapiens
UniProtKB
9497046
1.1.1.27
Ipomoea batatas
UniProtKB
19425
1.1.1.27
Lactobacillus brevis
UniProtKB
4333320
1.1.1.27
Lactobacillus casei
UniProtKB
11842236
1.1.1.27
Lactobacillus casei
UniProtKB
14601
1.1.1.27
Lactobacillus casei
UniProtKB
6411472
1.1.1.27
Lactobacillus curvatus
UniProtKB
14601
1.1.1.27
Lactobacillus helveticus
UniProtKB
9212432
1.1.1.27
Lactobacillus pentosus
UniProtKB
13815938
1.1.1.27
Lactobacillus plantarum
UniProtKB
-
1.1.1.27
Lactobacillus plantarum
UniProtKB
4333320
1.1.1.27
Lactococcus lactis
UniProtKB
12867459
1.1.1.27
Lactococcus lactis
UniProtKB
17944947
1.1.1.27
Lactococcus lactis subsp. cremoris
UniProtKB
11369999
1.1.1.27
Lactococcus lactis subsp. cremoris
UniProtKB
15006814
1.1.1.27
Lactococcus lactis subsp. cremoris
UniProtKB
251296
1.1.1.27
Lactococcus lactis subsp. cremoris
UniProtKB
805590
1.1.1.27
Lactococcus lactis subsp. lactis
UniProtKB
15006814
1.1.1.27
Lactococcus lactis subsp. lactis
UniProtKB
17595
1.1.1.27
Lactococcus lactis subsp. lactis
UniProtKB
6776093
1.1.1.27
Lactococcus lactis subsp. lactis
UniProtKB
9172349
1.1.1.27
Lactococcus lactis subsp. lactis
UniProtKB
9286977
1.1.1.27
Leuconostoc mesenteroides
UniProtKB
4333320
1.1.1.27
Meleagris gallopavo
UniProtKB
6022861
1.1.1.27
Molinema dessetae
UniProtKB
8897500
1.1.1.27
Mus musculus
UniProtKB
14114860
1.1.1.27
Mus musculus
UniProtKB
18721135
1.1.1.27
Oenococcus oeni
UniProtKB
4333320
1.1.1.27
Oryctolagus cuniculus
UniProtKB
14010189
1.1.1.27
Oryctolagus cuniculus
UniProtKB
14323584
1.1.1.27
Oryctolagus cuniculus
UniProtKB
1988948
1.1.1.27
Oryctolagus cuniculus
UniProtKB
6022861
1.1.1.27
Oryctolagus cuniculus
UniProtKB
8548923
1.1.1.27
Pediococcus damnosus
UniProtKB
234418
1.1.1.27
Pediococcus pentosaceus
UniProtKB
4333320
1.1.1.27
Phasianus colchicus
UniProtKB
6022861
1.1.1.27
Plasmodium berghei
UniProtKB
12967707
1.1.1.27
Plasmodium falciparum
UniProtKB
12967707
1.1.1.27
Plasmodium falciparum
UniProtKB
15117937
1.1.1.27
Plasmodium falciparum
UniProtKB
15147206
1.1.1.27
Plasmodium falciparum
UniProtKB
15317584
1.1.1.27
Plasmodium falciparum
UniProtKB
25693925
1.1.1.27
Plasmodium falciparum
UniProtKB
9497046
1.1.1.27
Plasmodium malariae
UniProtKB
15147206
1.1.1.27
Plasmodium ovale
UniProtKB
15147206
1.1.1.27
Plasmodium vivax
UniProtKB
15147206
1.1.1.27
Pterocnemia pennata
UniProtKB
6022861
1.1.1.27
Rana catesbeiana
UniProtKB
6022861
1.1.1.27
Rana perezi
UniProtKB
1714364
1.1.1.27
Rattus norvegicus
UniProtKB
6450416
1.1.1.27
Schistosoma mansoni
UniProtKB
2957147
1.1.1.27
Sphyraena argentea
UniProtKB
9115998
1.1.1.27
Sphyraena barracuda
UniProtKB
9115998
1.1.1.27
Sphyraena idiastes
UniProtKB
9115998
1.1.1.27
Sphyraena lucasana
UniProtKB
9115998
1.1.1.27
Squalus acanthias
UniProtKB
6022861
1.1.1.27
Streptococcus mutans
UniProtKB
2416689
1.1.1.27
Streptococcus mutans
UniProtKB
4336691
1.1.1.27
Streptococcus pyogenes
UniProtKB
-
1.1.1.27
Streptococcus pyogenes serotype M49
UniProtKB
-
1.1.1.27
Struthio camelus
UniProtKB
6022861
1.1.1.27
Sus scrofa
UniProtKB
15317584
1.1.1.27
Thunnus sp.
UniProtKB
6022861
1.1.1.27
Toxoplasma gondii
UniProtKB
11704270
1.1.1.27
Toxoplasma gondii
UniProtKB
14744130
1.1.1.28
Rattus norvegicus
UniProtKB
7929251
Pathways
Biosynthesis of secondary metabolites
Glycolysis/Gluconeogenesis
Metabolic pathways
Microbial metabolism in diverse environments
Pyruvate metabolism
External Links
KEGG-Pathway-ID
map01110
map00010
map01100
map01120
map00620
KEGG-Reaction-ID
R00703
MetaNetX-Reaction-ID
MNXR101040
Rhea-Reaction-ID
23447
23445
23446
23444
Reactome-Reaction-ID
R-DRE-70510
R-MMU-71849
R-OSA-71849
R-XTR-6807826
R-SSC-6807826
R-GGA-6807826
R-CFA-71849
R-CFA-70510
R-HSA-6807826
R-TGU-71849
R-TGU-70510
R-MMU-70510
R-DME-71849
R-SPO-71849
R-SPO-70510
R-MMU-6807826
R-CEL-71849
R-OSA-70510
R-XTR-70510
R-SPO-6807826
R-GGA-70510
R-GGA-71849
R-CEL-6807826
R-GGA-372910
R-HSA-71849
R-CEL-70510
R-ATH-71849
R-DRE-71849
R-RNO-71849
R-RNO-70510
R-DRE-6807826
R-DME-6807826
R-SSC-71849
R-BTA-71849
R-BTA-70510
R-TGU-6807826
R-HSA-70510
R-ATH-70510
R-SSC-70510
R-XTR-71849
R-OSA-6807826
R-GGA-372903
R-PFA-71849
R-PFA-6807826
R-ATH-6807826
R-PFA-70510
R-DME-70510
MetaCyc-Reaction-ID
L-LACTATE-DEHYDROGENASE-RXN
View all entries for reaction NAD+ + L-Lactate <-> Pyruvate + NADH + H+
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