Reaction Details
Reaction ID
88
Stochiometric Equation
5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate
Substrates
dUMP
5,10-Methylenetetrahydrofolate
Products
dTMP
Dihydrofolate
Enzymes known to
catalyse this reaction
(curated information)
EC Number
in Organism
UniProtKB Link
PubMedID
2.1.1.45
Bacillus subtilis
UniProtKB
418407
2.1.1.45
Bacteriophage T4
UniProtKB
2271601
2.1.1.45
Crithidia fasciculata
UniProtKB
14696
2.1.1.45
Escherichia coli
UniProtKB
10704192
2.1.1.45
Escherichia coli
UniProtKB
10841779
2.1.1.45
Escherichia coli
UniProtKB
14967040
2.1.1.45
Escherichia coli
UniProtKB
26612036
2.1.1.45
Escherichia coli
UniProtKB
3286637
2.1.1.45
Escherichia coli
UniProtKB
42538
2.1.1.45
Homo sapiens
UniProtKB
12859954
2.1.1.45
Homo sapiens
UniProtKB
2656695
2.1.1.45
Homo sapiens
UniProtKB
269853
2.1.1.45
Homo sapiens
UniProtKB
34155
2.1.1.45
Lactobacillus casei
UniProtKB
10704192
2.1.1.45
Lactobacillus casei
UniProtKB
10964985
2.1.1.45
Lactobacillus casei
UniProtKB
1284431
2.1.1.45
Lactobacillus casei
UniProtKB
1606134
2.1.1.45
Lactobacillus casei
UniProtKB
1627545
2.1.1.45
Lactobacillus casei
UniProtKB
2153960
2.1.1.45
Lactobacillus casei
UniProtKB
2182628
2.1.1.45
Lactobacillus casei
UniProtKB
413834
2.1.1.45
Lactobacillus casei
UniProtKB
8180187
2.1.1.45
Lactobacillus casei
UniProtKB
8378336
2.1.1.45
Lactobacillus casei
UniProtKB
9383465
2.1.1.45
Lactobacillus casei
UniProtKB
9398324
2.1.1.45
Leishmania major
UniProtKB
3597407
2.1.1.45
Leishmania major
UniProtKB
8144647
2.1.1.45
Leishmania tropica
UniProtKB
3922404
2.1.1.45
Rattus norvegicus
UniProtKB
3567221
2.1.1.45
Toxoplasma gondii
UniProtKB
12192007
2.1.1.45
Trypanosoma cruzi
UniProtKB
14696
2.1.1.45
Trypanosoma cruzi
UniProtKB
7969266
Pathways
Folate biosynthesis
Metabolic pathways
One carbon pool by folate
Pyrimidine metabolism
External Links
KEGG-Pathway-ID
map00790
map01100
map00670
map00240
KEGG-Reaction-ID
R02101
MetaNetX-Reaction-ID
MNXR104889
Rhea-Reaction-ID
12106
12107
12104
12105
View all entries for reaction 5,10-Methylenetetrahydrofolate + dUMP <-> dTMP + Dihydrofolate
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