Reaction Details



 Reaction ID 100
 Stochiometric Equation NADP+ + 5,6,7,8-Tetrahydrofolate <-> H+ + NADPH + Dihydrofolate
 Substrates
5,6,7,8-Tetrahydrofolate
NADP+
 Products
H+
Dihydrofolate
NADPH
 Enzymes known to
 catalyse this reaction
 (curated information)
EC Number in Organism UniProtKB Link PubMedID
1.5.1.3 Bos taurus UniProtKB 2322563
1.5.1.3 Crithidia fasciculata UniProtKB 4389070
1.5.1.3 Crithidia oncopelti UniProtKB 4389070
1.5.1.3 Enterococcus faecalis UniProtKB -
1.5.1.3 Enterococcus faecalis UniProtKB 4379861
1.5.1.3 Enterococcus faecium UniProtKB 2492521
1.5.1.3 Escherichia coli UniProtKB 11560482
1.5.1.3 Escherichia coli UniProtKB 12501195
1.5.1.3 Escherichia coli UniProtKB 14617668
1.5.1.3 Escherichia coli UniProtKB 15333636
1.5.1.3 Escherichia coli UniProtKB 15333637
1.5.1.3 Escherichia coli UniProtKB 15740745
1.5.1.3 Escherichia coli UniProtKB 1932013
1.5.1.3 Escherichia coli UniProtKB 1993166
1.5.1.3 Escherichia coli UniProtKB 2492521
1.5.1.3 Escherichia coli UniProtKB 3463995
1.5.1.3 Escherichia coli UniProtKB 8226776
1.5.1.3 Escherichia coli UniProtKB 8910413
1.5.1.3 Escherichia coli UniProtKB 9719595
1.5.1.3 Gallus gallus UniProtKB 2492521
1.5.1.3 Geobacillus stearothermophilus UniProtKB 16114879
1.5.1.3 Homo sapiens UniProtKB 19196009
1.5.1.3 Homo sapiens UniProtKB 19478082
1.5.1.3 Homo sapiens UniProtKB 2124504
1.5.1.3 Homo sapiens UniProtKB 2492521
1.5.1.3 Homo sapiens UniProtKB 4396284
1.5.1.3 Homo sapiens UniProtKB 7890613
1.5.1.3 Homo sapiens UniProtKB 9719595
1.5.1.3 Lactobacillus casei UniProtKB 18551641
1.5.1.3 Lactobacillus casei UniProtKB 2492521
1.5.1.3 Lactobacillus casei UniProtKB 2505841
1.5.1.3 Lactobacillus casei UniProtKB 3922404
1.5.1.3 Lactobacillus casei UniProtKB 7893701
1.5.1.3 Lactobacillus casei UniProtKB 9719595
1.5.1.3 Leishmania major UniProtKB 8144647
1.5.1.3 Leishmania major UniProtKB 8812831
1.5.1.3 Leishmania major UniProtKB 9153248
1.5.1.3 Leishmania major UniProtKB 9724534
1.5.1.3 Leishmania tarentolae UniProtKB 9153248
1.5.1.3 Leishmania tropica UniProtKB 3922404
1.5.1.3 Mus musculus UniProtKB 2492521
1.5.1.3 Mus musculus UniProtKB 3045118
1.5.1.3 Mus musculus UniProtKB 4396284
1.5.1.3 Plasmodium falciparum UniProtKB 17451822
1.5.1.3 Plasmodium falciparum UniProtKB 9207187
1.5.1.3 Pneumocystis carinii UniProtKB 19196009
1.5.1.3 Pneumocystis carinii UniProtKB 9719595
1.5.1.3 Pneumocystis jiroveci UniProtKB 19196009
1.5.1.3 Rattus norvegicus UniProtKB 4396284
1.5.1.3 Rattus norvegicus UniProtKB 9719595
1.5.1.3 Toxoplasma gondii UniProtKB 9719595
1.5.1.3 Trypanosoma brucei brucei UniProtKB 19748480
1.5.1.3 Trypanosoma brucei brucei UniProtKB 8538681
1.5.1.3 Trypanosoma cruzi UniProtKB 7969266
1.5.1.3 Trypanosoma cruzi UniProtKB 8920005
1.5.1.3 unknown prokaryotic organism UniProtKB 15182183
1.5.1.5 Pisum sativum UniProtKB 8304211
 Pathways Biosynthesis of cofactors
Folate biosynthesis
Metabolic pathways
One carbon pool by folate
 External Links
 KEGG-Pathway-ID map01240
map00790
map01100
map00670
 KEGG-Reaction-ID R00939
 MetaNetX-Reaction-ID MNXR97401
 Rhea-Reaction-ID 15009 15010 15011 15012
 Reactome-Reaction-ID R-CFA-197972 R-MMU-197972 R-SPO-197972 R-TGU-197972 R-GGA-197972 R-RNO-197972 R-HSA-197972 R-SSC-197972 R-DDI-197972 R-DRE-197972 R-XTR-197972 R-CEL-197972 R-DME-197972 R-BTA-197972 R-SCE-197972
 MetaCyc-Reaction-ID RXN-19329


View all entries for reaction NADP+ + 5,6,7,8-Tetrahydrofolate <-> H+ + NADPH + Dihydrofolate

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